Deoxynucleotide Triphosphates

July 11, 2023 1 Min read Views 50 BLOG

Deoxynucleotide triphosphates (dNTPs) are the nucleoside triphosphates containing deoxyribose. dNTPs are the essential building blocks of nucleic acid molecules, and as such are necessary components of PCR mixes as no new amplified DNA could be generated without them. The four individual deoxynucleotides which make up a DNA sequence including deoxyadenosine triphosphate (dATP), deoxythymidine triphosphate (dTTP), deoxycytosine triphosphate (dCTP) and deoxyguanosine triphosphate (dGTP). In addition, the quality of dNTPs also critical for the success of many key procedures such as PCR, cDNA synthesis, qPCR, sequencing, cloning and DNA labeling.

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