DNA Extraction Kits: A Beginner\’s Guide to Extracting DNA at Home

All cells contain DNA packaged within the nucleus. To extract the DNA, one needs to first break open the cell membrane or nucleus to access the DNA. DNA extraction kits work on the process of cell lysis where the cell membrane and nuclear membrane are disrupted using lysing solutions containing detergents. Once the cells are broken open, proteins are removed using proteinase K or other protein digesting enzymes. The proteins and other cell debris are then separated from the DNA using salt precipitation. This leaves behind a purified sample of extracted DNA.

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