Drug Eluting Balloon: A Revolution in Treating Peripheral Artery Disease

February 9, 2024 1 Min read Views 42 BLOG

When a DEB is inflated, the pressure causes the drugs coating to transfer onto the artery walls. Paclitaxel inhibits cell proliferation by arresting cells in the G0/G1 and G2/M phases of the cell cycle. This prevents smooth muscle cells from overcompensating after the angioplasty injury by growing abnormally. Studies show paclitaxel is taken up deeply into the arterial wall and remains present for over 30 days, significantly reducing the risk of restenosis.

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